The Coalition for Hemophilia B

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10 Things to Know About Donating Plasma

Curious to learn more about donating plasma?

Here are 10 fast facts from the Plasma Protein Therapeutics Association and CSL Behring.

  1. Plasma is the clear, straw-colored liquid portion of blood that remains after red blood cells, white blood cells, platelets and other cellular components are removed. The single largest component of human blood, it comprises about 55 percent, and contains water, salts, enzymes, antibodies and other proteins. 

  2. Plasma carries out a variety of functions in the body, including clotting blood, fighting diseases and other critical functions. 

  3. Source plasma donation and blood donation are critically important activities that contribute to saving lives. For many with rare diseases, these are the only therapies available to treat their chronic conditions. Your plasma can be used to create therapies that treat a variety of conditions and diseases, including hemophilia. 

  4. Plasma-derived therapies are also used in everyday medicine and emergency and critical care situations, as well as in preventive medicine. 

  5. Patients say they’re grateful to people who donate plasma. During the COVID-19 pandemic, patients who have primary immunodeficiencies and a rare disease called Alpha 1 Antitrypsin Deficiency have made personal pleas asking people to continue donating plasma. Meet additional patients who are helped by plasma-derived therapies. 

  6. Donors find meaning in donating plasma that will benefit patients who depend on plasma-derived medications. Meet a few donors and CSL employees who have shared their stories and reasons for donating plasma. 

  7. Source plasma is collected through a process called plasmapheresis. Plasmapheresis is a sterile, self-contained, automated process that separates plasma from red blood cells and other cellular components which are then returned to the donor.

  8. In general, plasma donors must be 18 years of age and weigh at least 110 pounds (50kg). All individuals must pass two separate medical examinations, a medical history screening and testing for transmissible viruses, before their donated plasma can be used to manufacture plasma protein therapies. Watch this short video to learn more about donating plasma. 

  9. Donating plasma takes time and commitment. To help ensure a safe and adequate supply of plasma, donors are provided with a modest stipend to recognize the substantial commitment of personal time and travel required to be a plasma donor. Each plasma collection facility sets its own compensation rates. 

  10. There are 900-plus licensed and certified plasma collection centers in the U.S., Canada, and Europe. Find a donor center near you, and donate today!